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1

Chaperone Activity of Bicyclic Nojirimycin Analogues for Gaucher Mutations in Comparison with N-(n-nonyl)Deoxynojirimycin

Zhuo Luan, Katsumi Higaki, Matilde Aguilar-Moncayo, Haruaki Ninomiya, Kousaku Ohno, M. Isabel García-Moreno, Carmen Ortiz Mellet, José M. García Fernández, Yoshiyuki Suzuki

Journal:

Year:

2009

Language:

english

File:

PDF, 482 KB

english, 2009

2

Cultural Difference in Conflict Management Strategies of Children and Its Development: Comparing 3- and 5-Year-Olds Across China, Japan, and Korea

Maruyama, Hiroki, Ujiie, Tatsuo, Takai, Jiro, Takahama, Yuko, Sakagami, Hiroko, Shibayama, Makoto, Fukumoto, Mayumi, Ninomiya, Katsumi, Hyang Ah, Park, Feng, Xiaoxia, Takatsuji, Chie, Hirose, Miwa, Ku

Journal:

Early Education and Development

Year:

2015

Language:

english

File:

PDF, 617 KB

english, 2015

3

Antisense suppression of TSC1 gene product, hamartin, enhances neurite outgrowth in NGF-treated PC12h cells

Florin Floricel, Katsumi Higaki, Hirotoshi Maki, Eiji Nanba, Haruaki Ninomiya, Kousaku Ohno

Journal:

Brain and Development

Year:

2007

Language:

english

File:

PDF, 1.32 MB

english, 2007

4

Progressive neuronal loss in the ventral posterior lateral and medial nuclei of thalamus in Niemann–Pick disease type C mouse brain

Atsuko Yamada, Makoto Saji, Yoko Ukita, Yoko Shinoda, Miyako Taniguchi, Katsumi Higaki, Haruaki Ninomiya, Kousaku Ohno

Journal:

Brain and Development

Year:

2001

Language:

english

File:

PDF, 2.38 MB

english, 2001

5

Endoplasmic Reticulum-associated Degradation of Niemann-Pick C1

Nakasone, Naoe, Nakamura, Yuko S., Higaki, Katsumi, Oumi, Nao, Ohno, Kousaku, Ninomiya, Haruaki

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.76 MB

english, 2014

6

HER2-Positive Metaplastic Spindle Cell Carcinoma Associated with Synchronous Bilateral Apocrine Carcinoma of the Breast

Kito, Katsumi, Maeda, Toshiharu, Ninomiya, Keiko, Sugita, Atsuro, Sagawa, Teiri, Matsuoka, Kinya, Kinoshita, Kousei, Hyodo, Naoki, Morita, Nagisa, Furuya, Keizo

Journal:

Case Reports in Pathology

Year:

2014

Language:

english

File:

PDF, 8.26 MB

english, 2014

7

Comparison of Privacy Consciousness Between Younger and Older Adults

Tabata, Naoya, Sato, Hirotsune, Ninomiya, Katsumi

Journal:

Japanese Psychological Research

Year:

2020

File:

PDF, 196 KB

2020

8

Molecular Basis of 1-Deoxygalactonojirimycin Arylthiourea Binding to Human α-Galactosidase A: Pharmacological Chaperoning Efficacy on Fabry Disease Mutants

Yu, Yi, Mena-Barragán, Teresa, Higaki, Katsumi, Johnson, Jennifer L., Drury, Jason E., Lieberman, Raquel L., Nakasone, Naoe, Ninomiya, Haruaki, Tsukimura, Takahiro, Sakuraba, Hitoshi, Suzuki, Yoshiyuk

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.70 MB

english, 2014

9

Effects of High-voltage Electric Field Treatment on the Water Activity of Bread

Esaki, Kimiko, Ninomiya, Fumiko, Hisaki, Kumiko, Higasa, Takahiko, Shibata, Katsumi, Murata, Kousaku, Aibara, Shigeo

Journal:

Bioscience Biotechnology and Biochemistry

Year:

1996

Language:

english

File:

PDF, 1.11 MB

english, 1996

10

Restoration of mutant hERG stability by inhibition of HDAC6

Li, Peili, Kurata, Yasutaka, Endang, Mahati, Ninomiya, Haruaki, Higaki, Katsumi, Taufiq, Fikri, Morikawa, Kumi, Shirayoshi, Yasuaki, Horie, Minoru, Hisatome, Ichiro

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2018

Language:

english

File:

PDF, 1.93 MB

english, 2018

11

An Intratracheal Instillation Bioassay System for Detection of Lung Toxicity Due to Fine Particles in F344 Rats

Yokohira, Masanao, Kuno, Toshiya, Yamakawa, Keiko, Hashimoto, Nozomi, Ninomiya, Fumiko, Suzuki, Satoshi, Saoo, Kousuke, Imaida, Katsumi

Journal:

Journal of Toxicologic Pathology

Year:

2009

Language:

english

File:

PDF, 437 KB

english, 2009

12

Chemical and chemotaxonomic researches for pterophyten 52. Components of Scypholepia hookerianaJ.Sm.

KURAISHI, TADAYUKI, NINOMIYA, KATSUMI, MURAKAMI, TAKAO, TANAKA, NOBUTOSHI, SAIKI, YASUHISA, CHEN, CHIUMING

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1984

File:

PDF, 1.02 MB

1984

13

ChemInform Abstract: NONOXIDATIVE PHOTOCYCLIZATION OF 2-AROYL-1-METHYLENE-1,2,3,4-TETRAHYDROISOQUINOLINES

NAITO, T., KATSUMI, K., TADA, Y., NINOMIYA, I.

Journal:

Chemischer Informationsdienst

Year:

1983

File:

PDF, 117 KB

1983

14

Metabolic Fate of Ritipenem Acoxil (1): Absorption, Distribution, Metabolism and Excretion in Rats and Dogs.

ESUMI, Yoshio, NINOMIYA, Shin-ichi, SEKI, Hideaki, UOHAMA, Katsumi, KIMURA, Satoru, TANAKA, Masayoshi, HATSUOKA, Masanori

Journal:

Drug Metabolism and Pharmacokinetics

Year:

1996

Language:

english

File:

PDF, 11.31 MB

english, 1996

15

Stabilization of Kv1.5 channel protein by the inotropic agent olprinone

Endo, Ryo, Kurata, Yasutaka, Notsu, Tomomi, Li, Peili, Morikawa, Kumi, Kondo, Takehito, Ogura, Kazuyoshi, Miake, Junichiro, Yoshida, Akio, Shirayoshi, Yasuaki, Ninomiya, Haruaki, Higaki, Katsumi, Kuwa

Journal:

European Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 993 KB

english, 2015

16

Metabolic Fate of Ritipenem Acoxil (2): Absorption, Distribution, Metabolism and Excretion in Rats After Repeated Administration.

ESUMI, Yoshio, NINOMIYA, Shin-ichi, SEKI, Hideaki, UOHAMA, Katsumi, GUNJI, Shinobu, KIMURA, Satoru, TANAKA, Masayoshi, HATSUOKA, Masanori

Journal:

Drug Metabolism and Pharmacokinetics

Year:

1996

File:

PDF, 6.10 MB

1996

17

Genotype/phenotype of 6 Chinese cases with Niemann–Pick disease type C

Hui Xiong, Katsumi Higaki, Cui-jie Wei, Xin-Hua Bao, Yue-Hua Zhang, Na Fu, Jiong Qin, Kaori Adachi, Yumiko Kumura, Haruaki Ninomiya, Eiji Nanba, Xi-Ru Wu

Journal:

Year:

2012

Language:

english

File:

PDF, 290 KB

english, 2012

18

Neuromagnetic gamma-band activity in the primary and secondary somatosensory areas

Ihara, Aya, Hirata, Masayuki, Yanagihara, Keiko, Ninomiya, Hirotomo, Imai, Katsumi, Ishii, Ryouhei, Osaki, Yasuhiro, Sakihara, Kotoe, Izumi, Hiromi, Imaoka, Hiroyuki, Kato, Amami, Yoshimine, Toshiki,

Journal:

Year:

2003

Language:

english

File:

PDF, 195 KB

english, 2003

19

Protective Effect of Neurotropin Against Lipopolysaccharide-Induced Hypotension and Lethality Linked to Suppression of Inducible Nitric Oxide Synthase Induction

Higaki, Katsumi, Ninomiya, Haruaki, Saji, Makoto, Maki, Hirotoshi, Koike, Tomohiro, Ohno, Kousaku

Journal:

The Japanese Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 577 KB

english, 2001

20

Estimation by In-Situ Measurement of Excavation Disturbance by Blasting in Sedimentary Soft Rock.

Sugihara, Kozo, Kamemura, Katsumi, Ninomiya, Yasuo

Journal:

Doboku Gakkai Ronbunshu

Year:

1998

File:

PDF, 1.87 MB

1998

21

Lysosomal accumulation of Trk protein in brain of GM1-gangliosidosis mouse and its restoration by chemical chaperone

Ayumi Takamura, Katsumi Higaki, Haruaki Ninomiya, Tomoko Takai, Junichiro Matsuda, Masami Iida, Kousaku Ohno, Yoshiyuki Suzuki, Eiji Nanba

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 910 KB

english, 2011

22

E3 ligase CHIP and Hsc70 regulate Kv1.5 protein expression and function in mammalian cells

Li, Peili, Kurata, Yasutaka, Maharani, Nani, Mahati, Endang, Higaki, Katsumi, Hasegawa, Akira, Shirayoshi, Yasuaki, Yoshida, Akio, Kondo, Tatehito, Kurozawa, Youichi, Yamamoto, Kazuhiro, Ninomiya, Har

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 2.24 MB

english, 2015

23

Establishment of a Stroma-Dependent Human Acute Myelomonocytic Leukemia Cell Line, NAMO-2, with FLT3 Tandem Duplication

Akihiro Abe, Hitoshi Kiyoi, Manabu Ninomiya, Tomio Yamazaki, Takuhei Murase, Kazutaka Ozeki, Momoko Suzuki, Fumihiko Hayakawa, Akira Katsumi, Nobuhiko Emi, Tomoki Naoe

Journal:

International Journal of Hematology

Year:

2006

Language:

english

File:

PDF, 1.03 MB

english, 2006

24

Rat strain differences in levels and effects of chronic inflammation due to intratracheal instillation of quartz on lung tumorigenesis induced by DHPN

Nakano, Yuko, Yokohira, Masanao, Hashimoto, Nozomi, Yamakawa, Keiko, Kishi, Sosuke, Ninomiya, Fumiko, Kanie, Shohei, Saoo, Kousuke, Imaida, Katsumi

Journal:

Experimental and Toxicologic Pathology

Year:

2014

Language:

english

File:

PDF, 1.29 MB

english, 2014

25

Candidate molecules for chemical chaperone therapy of G M1 -gangliosidosis

Higaki, Katsumi, Ninomiya, Haruaki, Suzuki, Yoshiyuki, Nanba, Eiji

Journal:

Future Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

26

ChemInform Abstract: Syntheses of 24,25-Dihydroxyvitamin D2 (I), 24,25-Dihydroxy-22-dehydrovitamin D3 (II), 25-Hydroxy-24-oxo-22-dehydrovitamin D3 (III), and 22,24,25-Trihydroxyvitamin D3 (IV).

KATSUMI, K., OKANO, T., ONO, Y., MAEGAKI, E., NISHIMURA, K., BABA, M., KOBAYASHI, T., MIYATA, O., NAITO, T., NINOMIYA, I.

Journal:

Year:

1987

File:

PDF, 101 KB

1987

27

Syntheses of 24,25-dihydroxyvitamin D2, 24,25-dihydroxy-22-dehydrovitamin D3, 25-hydroxy-24-oxo-22-dehydrovitamin D3 and 22,24,25-trihydroxyvitamin D3.

KATSUMI, KOTOMI, OKANO, TOSHIO, ONO, YURIE, MAEGAKI, EMIKO, NISHIMURA, KUMIKO, BABA, MIZUE, KOBAYASHI, TADASHI, MIYATA, OKIKO, NAITO, TAKEAKI, NINOMIYA, ICHIYA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 1.45 MB

english, 1987

28

Synthesis of diastereomeric 24,25-dihydroxyvitamin D2 and separation of its (24R)- and (24S)-isomers.

Katsumi, Kotomi, Okano, Toshio, Kobayashi, Tadashi, Miyata, Okiko, Naito, Takeaki, Ninomiya, Ichiya

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1984

File:

PDF, 351 KB

1984

29

Multiple hypervascular liver nodules in a heavy drinker of alcohol

SOO RYANG KIM, YOKO MAEKAWA, TOSHIAKI NINOMIYA, SUSUMU IMOTO, TOSHIYUKI MATSUOKA, KENJI ANDO, KEIJI MITA, KWANSONG KU, TOSHIHIRO KOTERAZAWA, TAISUKE NAKAJIMA, KATSUMI FUKUDA, YOSHIHIKO YANO, MIYUKI NA

Journal:

Journal of Gastroenterology and Hepatology

Year:

2005

Language:

english

File:

PDF, 323 KB

english, 2005

30

Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone

Sayuri Suzuki, Yasutaka Kurata, Peili Li, Tomomi Notsu, Akira Hasegawa, Nobuhito Ikeda, Masaru Kato, Junichiro Miake, Shinji Sakata, Goshi Shiota, Akio Yoshida, Haruaki Ninomiya, Katsumi Higaki, Kazuh

Journal:

European Journal of Pharmacology

Year:

2012

Language:

english

File:

PDF, 753 KB

english, 2012

31

Comparison of privacy consciousness between Japanese and Taiwanese

Tabata, Naoya, Sato, Hirotsune, Ninomiya, Katsumi, Yamamoto, Chika

Journal:

Year:

2018

Language:

english

File:

PDF, 100 KB

english, 2018

32

NPC1 gene mutations in Japanese patients with Niemann-Pick disease type

Toshiyuki Yamamoto, Eiji Nanba, Haruaki Ninomiya, Katsumi Higaki, Miyako Taniguchi, Haidi Zhang, Shinjiro Akaboshi, Yasuhiro Watanabe, Takao Takeshima, Koji Inui, Shintaro Okada, Akemi Tanaka, Norio S

Journal:

Year:

1999

Language:

english

File:

PDF, 171 KB

english, 1999

33

N-Octyl-β-valienamine up-regulates activity of F213I mutant β-glucosidase in cultured cells: a potential chemical chaperone therapy for Gaucher disease

Hou Lin, Yuko Sugimoto, Yuki Ohsaki, Haruaki Ninomiya, Akira Oka, Miyako Taniguchi, Hiroyuki Ida, Yoshikatsu Eto, Seiichiro Ogawa, Yuji Matsuzaki, Miwa Sawa, Takehiko Inoue, Katsumi Higaki, Eiji Nanba

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2004

Language:

english

File:

PDF, 510 KB

english, 2004

34

One-year chronic toxicity study of Aloe arborescens Miller var. natalensis Berger in Wistar Hannover rats. A pilot study

Yoko Matsuda, Masanao Yokohira, Satoshi Suzuki, Kyoko Hosokawa, Keiko Yamakawa, Yu Zeng, Fumiko Ninomiya, Kousuke Saoo, Toshiya Kuno, Katsumi Imaida

Journal:

Food and Chemical Toxicology

Year:

2008

Language:

english

File:

PDF, 148 KB

english, 2008

35

A Bicyclic 1-Deoxygalactonojirimycin Derivative as a Novel Pharmacological Chaperone for GM1 Gangliosidosis

Takai, Tomoko, Higaki, Katsumi, Aguilar-Moncayo, Matilde, Mena-Barragán, Teresa, Hirano, Yuki, Yura, Kei, Yu, Liang, Ninomiya, Haruaki, García-Moreno, M. Isabel, Sakakibara, Yasubumi, Ohno, Kousaku, N

Journal:

Molecular Therapy

Year:

2013

Language:

english

File:

PDF, 637 KB

english, 2013

36

MiR-139-5p is associated with inflammatory regulation through c-FOS suppression, and contributes to the progression of primary biliary cholangitis

Katsumi, Tomohiro, Ninomiya, Masashi, Nishina, Taketo, Mizuno, Kei, Tomita, Kyoko, Haga, Hiroaki, Okumoto, Kazuo, Saito, Takafumi, Shimosegawa, Tooru, Ueno, Yoshiyuki

Journal:

Laboratory Investigation

Year:

2016

Language:

english

File:

PDF, 4.27 MB

english, 2016

37

Secondary ion yields for vacuum-type electrospray droplet beams measured with a triple focus time-of-flight analyzer

Ninomiya, Satoshi, Sakai, Yuji, Watanabe, Ryo, Sogou, Mauo, Miyayama, Takuya, Sakai, Daisuke, Watanabe, Katsumi, Chen, Lee Chuin, Hiraoka, Kenzo

Journal:

Rapid Communications in Mass Spectrometry

Year:

2016

Language:

english

File:

PDF, 357 KB

english, 2016

38

Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice

Ninomiya, M, Abe, A, Katsumi, A, Xu, J, Ito, M, Arai, F, Suda, T, Ito, M, Kiyoi, H, Kinoshita, T

Journal:

Year:

2006

Language:

english

File:

PDF, 416 KB

english, 2006

39

Strain differences in pleural mesothelial cell reactions induced by potassium octatitanate fibers (TISMO) infused directly into the thoracic cavity

Yokohira, Masanao, Nakano, Yuko, Yamakawa, Keiko, Kishi, Sosuke, Ninomiya, Fumiko, Saoo, Kousuke, Imaida, Katsumi

Journal:

Experimental and Toxicologic Pathology

Year:

2013

Language:

english

File:

PDF, 3.49 MB

english, 2013

40

A Fluorescent sp2-Iminosugar With Pharmacological Chaperone Activity for Gaucher Disease: Synthesis and Intracellular Distribution Studies

Dr. Zhuo Luan , Dr. Katsumi Higaki, Dr. Matilde Aguilar-Moncayo, Linjing Li, Prof. Haruaki Ninomiya, Prof. Eiji Nanba, Prof. Kousaku Ohno, Dr. M. Isabel García-Moreno, Prof. Carmen Ortiz Mellet, Prof

Journal:

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

41

Chemical chaperone therapy: Luciferase assay for screening of β-galactosidase mutations

Linjing Li, Katsumi Higaki, Haruaki Ninomiya, Zhuo Luan, Masami Iida, Seiichiro Ogawa, Yoshiyuki Suzuki, Kousaku Ohno, Eiji Nanba

Journal:

Molecular Genetics and Metabolism

Year:

2010

Language:

english

File:

PDF, 540 KB

english, 2010

42

The TSC1 gene product hamartin interacts with NADE

Sakiko Yasui, Kokoro Tsuzaki, Haruaki Ninomiya, Florin Floricel, Yasuo Asano, Hirotoshi Maki, Ayumi Takamura, Eiji Nanba, Katsumi Higaki, Kousaku Ohno

Journal:

Molecular and Cellular Neuroscience

Year:

2007

Language:

english

File:

PDF, 1.25 MB

english, 2007

43

Toxicity of Nicotine by Repeated Intratracheal Instillation to F344 Rats

Yokohira, Masanao, Nakano, Yuko, Hashimoto, Nozomi, Yamakawa, Keiko, Ninomiya, Fumiko, Kishi, Sosuke, Saoo, Kousuke, Imaida, Katsumi

Journal:

Journal of Toxicologic Pathology

Year:

2012

Language:

english

File:

PDF, 4.14 MB

english, 2012

44

Immunohistochemical Characteristics of Surfactant Proteins A, B, C and D in Inflammatory and Tumorigenic Lung Lesions of F344 Rats

Yokohira, Masanao, Yamakawa, Keiko, Nakano, Yuko, Numano, Takamasa, Furukawa, Fumio, Kishi, Sosuke, Ninomiya, Fumiko, Kanie, Shohei, Hitotsumachi, Hiroko, Saoo, Kousuke, Imaida, Katsumi

Journal:

Journal of Toxicologic Pathology

Year:

2014

Language:

english

File:

PDF, 3.86 MB

english, 2014

45

ChemInform Abstract: SYNTHESIS OF DIASTEREOMERIC 24,25-DIHYDROXYVITAMIN D2 AND SEPARATION OF ITS (24R)- AND (24S)-ISOMERS

KATSUMI, K., OKANO, T., KOBAYASHI, T., MIYATA, O., NAITO, T., NINOMIYA, I.

Journal:

Chemischer Informationsdienst

Year:

1985

File:

PDF, 172 KB

1985

46

Pterosin-derivate aus der familie pteridaceae

Takao Murakami, Toshiko Satake, Katsumi Ninomiya, Hideki Iida, Kazuhiko Yamauchi, Nobutoshi Tanaka, Yasuhisa Saiki, Chiu-Ming Chen

Journal:

Year:

1980

File:

PDF, 334 KB

1980

47

Synthetic aperture magnetometry analysis of epileptic fast oscillation of MEG

Hirotomo Ninomiya, Amami Kato, Masayuki Hirata, Masaaki Taniguchi, Haruhiko Kijima, Junji Yamada, Shunichiro Hirano, Katsumi Imai, Toshiki Yoshimine

Journal:

International Congress Series

Year:

2002

Language:

english

File:

PDF, 480 KB

english, 2002

48

Use of ADME studies to confirm the safety of ε-polylysine as a preservative in food

Jun Hiraki, Takafumi Ichikawa, Shin-ichi Ninomiya, Hideaki Seki, Katsumi Uohama, Hiroshi Seki, Shigemi Kimura, Yukio Yanagimoto, James W Barnett Jr.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2003

Language:

english

File:

PDF, 241 KB

english, 2003

49

The effect of a high fat diet on pyruvate decarboxylase deficiency without central nervous system involvement

Kodama, Soichi, Yagi, Ryuzaburo, Ninomiya, Michindo, Goji, Katsumi, Takahashi, Toshikazu, Morishita, Yorihiko, Matsuo, Tamotsu

Journal:

Brain and Development

Year:

1983

Language:

english

File:

PDF, 710 KB

english, 1983

50

Increased NPC1 mRNA in skin fibroblasts from Niemann-Pick disease type C patients

Toshiyuki Yamamoto, Jian-Hua Feng, Katsumi Higaki, Miyako Taniguchi, Eiji Nanba, Haruaki Ninomiya, Kousaku Ohno

Journal:

Brain and Development

Year:

2004

Language:

english

File:

PDF, 284 KB

english, 2004

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